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[Risk of lymph node metastasis in superficial esophageal cancer]

½Äµµ¾ÏÀÇ ³»½Ã°æ Áø´Ü¿¡ ´ëÇÑ ½Ã¸®Á ½ÃÀÛÇϱ⿡ ¾Õ¼­ ¸²ÇÁÀý ÀüÀÌ¿¡ ´ëÇÏ¿© ´Ù½Ã Çѹø »ìÆ캸´Â °ÍÀº Àǹ̰¡ ÀÖÀ» µí ÇÕ´Ï´Ù. Áö³­ 12¿ù 23ÀÏ EndoTODAY¿¡¼­ ¼³¸íµå¸° ¹Ù ÀÖÁö¸¸ ½Äµµ¿¡¼­´Â Á¡¸·¾ÏÀ̳ª Á¡¸·ÇϾÏÀÇ ¸²ÇÁÀý ÀüÀÌ À§ÇèÀÌ À§³ª ´ëÀ庸´Ù ÈξÀ ³ô±â ¶§¹®ÀÔ´Ï´Ù. 2008³â º» ±³½ÇÀÇ ³í¹®¿¡¼­ Á¦½ÃÇÑ ÀڷḦ ±×¸²À¸·Î Á¤¸®ÇÏ¸é ¾Æ·¡¿Í °°½À´Ï´Ù. °ËÀº Á¡ÀÌ ¸²ÇÁÀý ÀüÀÌ°¡ ÀÖ¾ú´ø Áõ·ÊÀÔ´Ï´Ù.

M3 ¾Ï¿¡¼­µµ ¸²ÇÁÀý À§ÇèÀÌ »ó´çÈ÷ ³ô´Ù´Âµ¥ À¯ÀÇÇØ¾ß ÇÏ°Ú½À´Ï´Ù. ¿¬±¸ ±â°£ ´ë»óȯÀÚ¿¡¼­´Â ¾ø¾úÁö¸¸, °£È¤ M2¾Ï¿¡¼­ ¸²ÇÁÀý ÀüÀ̸¦ º¸ÀÌ´Â Áõ·Ê¸¦ ¸¸³ª±âµµ ÇÕ´Ï´Ù.


[½Äµµ¾Ï ȯÀÚÀÇ ¸²ÇÁÀý ¸í¸í¹ý]

1. ½Äµµ squamous cell carcinomaÀÇ ¸²ÇÁÀý ÀüÀÌ À§Çè

½Äµµ squamous cell carcinomaÀÇ ¸²ÇÁÀý ÀüÀÌ À§ÇèÀº À§³ª ´ëÀ庸´Ù ÈξÀ ³ô½À´Ï´Ù (EndoTODAY 20121223). ¼ö ³â Àü »ï¼º¼­¿ïº´¿øÀÇ ÀڷḦ ºÐ¼®ÇÑ ¹Ù ÀÖ½À´Ï´Ù (Kim DU. J Gastroenterol Hepatol 2008). ÇÙ½É ±×·¥À» ¾Æ·¡¿¡ ¿Å±é´Ï´Ù.

M3 ¾Ï¿¡¼­µµ ¸²ÇÁÀý À§ÇèÀÌ »ó´çÈ÷ ³ô´Ù´Âµ¥ À¯ÀÇÇØ¾ß ÇÏ°Ú½À´Ï´Ù. ¿¬±¸ ±â°£ ´ë»óȯÀÚ¿¡¼­´Â ¾ø¾úÁö¸¸, °£È¤ M2¾Ï¿¡¼­ ¸²ÇÁÀý ÀüÀ̸¦ º¸ÀÌ´Â Áõ·Ê¸¦ ¸¸³ª±âµµ ÇÕ´Ï´Ù.


2. ½Äµµ¾Ï ȯÀÚÀÇ ¸²ÇÁÀý ¸í¸í¹ý

½Äµµ¾Ï ȯÀÚÀÇ ¸²ÇÁÀý ¸í¸í¹ýÀº Å©°Ô ¼­¾ç½Ä(AJCC)°ú ÀϺ»½Ä(ÀϺ»½ÄµµÁúȯÇÐȸ, ÀϺ»À§¾ÏÇÐȸ)ÀÌ ÀÖ½À´Ï´Ù.

1) AJCC 7ÆÇ¿¡ µû¸¥ ¸²ÇÁÀý ¸í¸í¹ý

1L = left supraclavicular, 1R = right supraclavicular, 2L = left upper paratracheal, 2R = right upper paratracheal, 4L = left lower paratracheal, 4R = right lower paratracheal, 5 = aortopulmonary, 6 = anterior mediastinal, 7 = subcarinal, 8L = lower paraesophageal, 8M = middle paraesophageal, 9 = pulmonary ligament, 10L = left tracheobronchial, 10R = right tracheobronchial, 15 = diaphragmatic, 16 = paracardial, 17 = left gastric, 18 = common hepatic, 19 = splenic, 20 = celiac. The posterior mediastinal lymph node (3P) is not shown.


2) ÀϺ» ½ÄµµÁúȯÇÐȸ ¸²ÇÁÀý ¸í¸í¹ý (Esophagus 2004;1:61-88)


3) ÀϺ» À§¾ÏÇÐȸ ¸²ÇÁÀý ¸í¸í¹ý

17 = lymph nodes on the anterior surface of the pancreatic head, 18 = lymph nodes along the inferior margin of the pancreas, 19 = lnfradiaphragmatic lymph nodes, 20 = lymph nodes in the esophagus hiatus of the diaphragm, 110 = lower throacic paraesophageal nodes, 111 = supradiaphragmatic lymph nodes, 112 = posterior mediastinal nodes


4) ¼­¾ç½Ä°ú ÀϺ»½ÄÀÇ ºñ±³

Barrett adenocarcinoma³ª cardia cancerÀÇ ¼ö¼ú¿¡ ´ëÇÏ¿© ÈäºÎ¿Ü°ú³ª ÀϹݿܰú ÀÇ»ç¿Í ´ëÈ­ÇÒ ¶§ ¸²ÇÁÀý ¹Ú¸® ¹üÀ§¸¦ ³íÇϱâ´Â ½±Áö ¾Ê½À´Ï´Ù. ƯÈ÷ ÈäºÎ¿Ü°ú¿¡¼­ »ç¿ëÇÏ´Â ¿ë¾î¿Í ÀϹݿܰú¿¡¼­ »ç¿ëÇÏ´Â ¿ë¾î°¡ ´Ù¸£±â ¶§¹®ÀÔ´Ï´Ù. ÈäºÎ¿Ü°ú¿¡¼­´Â ¹Ì±¹½Ä ¼ýÀÚ¸¦ »ç¿ëÇÏ°í ÀϹݿܰú¿¡¼­´Â ÀϺ»½Ä ¼ýÀÚ¸¦ »ç¿ëÇϱ⠶§¹®ÀÔ´Ï´Ù. ¿¹¸¦ µé¾î lower paratracheal nodes´Â ¹Ì±¹½ÄÀ¸·Î´Â 8L¹ø, ÀϺ»½ÄÀ¸·Î´Â 110¹øÀÔ´Ï´Ù.

À§Ä¡¼­¾ç½ÄÀϺ»½Ä
Lower paratracheal nodes8L110
Diaphragmatic nodes15111
Paracardial nodes161 (éÓ) ¶Ç´Â 2 (ñ§)


3. ½Äµµ¾Ï ȯÀÚÀÇ º¹ºÎ ¸²ÇÁÀý ¸í¸í¹ý

½Äµµ¾Ï ȯÀÚÀÇ º¹ºÎ ¸²ÇÁÀýÀº º´¿ø¿¡¼­ º°µµÀÇ À̸§À» ºÎ¿©ÇÏ¿© °ü¸®Çϱ⵵ ÇÕ´Ï´Ù. »ï¼º¼­¿ïº´¿ø¿¡¼­´Â ¾Æ·¡¿Í °°Àº ÀÚüÀûÀ¸·Î Á¤ÀÇÇÑ ±ÔÄ¢À¸·Î ¸í¸íÇϱ⵵ ÇÕ´Ï´Ù. ¼ö¼ú±â·ÏÁö µî¿¡¼­ ÀÌ¿ëÇÏ°í ÀÖ½À´Ï´Ù.


[References]

1) Takubo K. Histopathological diagnosis of adenocarcinoma in Barrett's esophagus. Dig Endosc 2014;26:322-30.

© ÀÏ¿ø³»½Ã°æ±³½Ç ¹Ù¸¥³»½Ã°æ¿¬±¸¼Ò ÀÌÁØÇà. EndoTODAY Endoscopy Learning Center. Lee Jun Haeng.