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[20110203. Chromoendoscopy (14) - Indigo carmine or indigo-carmine?]

Indigo carmineÀº Á¦°¡ °¡Àå »ç¶ûÇÏ´Â »ö¼ÒÀÔ´Ï´Ù. °ÅÀÇ ¸ÅÀÏ »ç¿ëÇÏ°í ÀÖ½À´Ï´Ù. ´ÙÀ½Àº ·ç°ñ¾×ÀÔ´Ï´Ù. ±×·¯³ª »ç¿ë ºóµµ°¡ ´Ù¸¨´Ï´Ù. Indigo carmineÀÌ ¾ø´Â ESD´Â »ý°¢¸¸ Çصµ ²ûÁ÷ÇÕ´Ï´Ù. ±×·±µ¥ Àú´Â ¾ÆÁ÷ indigo carmineÀÇ Á¤È®ÇÑ ±â¿øÁ¶Â÷ ¸ð¸¨´Ï´Ù. Ȥ½Ã Á¤È®ÇÑ Á¤º¸¸¦ °¡Áö½Å ºÐÀº Á¦°Ô ¿¬¶ôÁֽñ⠹ٶø´Ï´Ù.

Á¦°¡ ¹è¿ì±â·Î´Â indigo´Â Ǫ¸¥ ½Ä¹°¼º »ö¼ÒÀÌ°í carmineÀº ºÓÀº µ¿¹°¼º »ö¼Ò(red coloring agent from eggs of female cochinea, a tropical insect from Mexico)ÀÔ´Ï´Ù. À̸¦ ¼¯Àº °ÍÀÌ indigo carmineÀ̶ó°í ¹è¿ü½À´Ï´Ù. ±×·±µ¥ ÃÖ±Ù WikipediaµîÀ» ã¾Æº¸´Ï indigo dyeÀÇ sulfonated formÀ» indigo carmineÀ̶ó°í ºÎ¸£¸ç Saxon blue¿Í °°Àº ¸»À̾ú½À´Ï´Ù. Á¤½Ä ¸íĪÀº 5,5'-indigotindisulfonate sodiumÀÌ¸ç ±¸Á¶½ÄÀº C16H8N2Na2O8S2ÀÔ´Ï´Ù (ÂüÁ¶: NCBI PubChem). pH 11.4¿¡¼­ Ǫ¸¥»öÀ¸·Î pH 13¿¡¼­ ³ë¶õ»öÀ¸·Î º¯Çϴ Ư¡ÀÌ À־ pH indicator·Î »ç¿ëµÈ´Ù°í ÇÏ¿´½À´Ï´Ù.

À̸§µµ ¸íÈ®ÇÏÁö ¾Ê½À´Ï´Ù. Ingido carmine, indigocarmine (¶ç¾î ¾²±â ¾øÀ½), indigo-carmine (hyphen ÀÖÀ½), Indigo Carmine (¶ç¾î ¾²±â ÀÖ°í ´ë¹®ÀÚ) Áß ¾î¶² °ÍÀÌ ¿ÇÀºÁö ¸ð¸£°Ú½À´Ï´Ù. º¸Åë indigo carmine (¶ç¾î ¾²±â ÀÖ°í ¼Ò¹®ÀÚÀÌ°í hyphen ¾øÀ½)À̶ó°í ¾¹´Ï´Ù. ¾Æ¸¶ ÀÌ°Ô ¸ÂÀ» °ÍÀÔ´Ï´Ù.

ÀÇÇп¡¼­ indigo carmineÀÇ ¿ëµµ´Â ´Ù¾çÇÕ´Ï´Ù. °ú°Å¿¡´Â renal function test ¿ëÀ¸·Î Á¾Á¾ »ç¿ëµÇ¾ú½À´Ï´Ù. ºÎÀÛ¿ëÀ¸·Î´Â bradycardia, hypertension, bronchospasm, urticaria µîÀÌ °¡´ÉÇѵ¥ ÁÖ·Î Á¤¸ÆÁֻ翡¼­ ³ªÅ¸³³´Ï´Ù. À§³»½Ã°æ½Ã ºÐ¹«ÇÏ¿© ³ªÅ¸³ª´Â °Í °°Áö´Â ¾Ê½À´Ï´Ù. ±×·¯³ª ÁÖÀÇÇؼ­ ³ª»Ü °ÍÀº ¾ø½À´Ï´Ù. »ý°¢ÄÁµ¥ ESD¸¦ Çϸ鼭 ´Ù·® »ç¿ëÇÏ¸é ºÎÀÛ¿ëÀÌ ³ªÅ¸³¯Áö ¸ð¸¨´Ï´Ù. ±×·¯³ª ½ÇÁ¦ º¸°íµÈ °ÍÀ» º¸Áö´Â ¸øÇß½À´Ï´Ù.

Indigo carmineÀÇ °¡Àå Å« ¹®Á¦Á¡Àº '°£È¤ °ø±ÞÀÌ ²÷±ä´Ù'´Â °ÍÀÔ´Ï´Ù. ´ë¿ëÀ¸·Î methylene blue¸¦ ¾²°í ÀÖ½À´Ï´Ù. ÀÌ°¡ ¾øÀ¸¸é ÀÕ¸öÀÔ´Ï´Ù.


@ ¸µÅ©: »ö¼Ò³»½Ã°æ chromoendoscopy

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